Contraindications to Cialis
List of Cialis contraindications is not so enormous. Cialis is safe for the majority of men worldwide. Let’s grapple with the contraindications with My Canadian Pharmacy staff.
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Main Contraindications
The main contraindications are:
- hypersensitivity to tadalafil or to any substance that is a part of the drug;
- in case of taking drugs containing any organic nitrates;
- use of persons under 18 years old;
- contraindications presence to sexual activity in patients with diseases of cardiovascular system: myocardial infarction within the past 90 days, unstable angina, occurrence of angina attack during intercourse, chronic heart failure II-IV according to NYHA classification, uncontrolled arrhythmia, hypotension (arterial blood pressure less than 90/50 mmHg), uncontrolled hypertension, ischemic stroke within the last 6 months;
- loss of vision because of anterior ischemic optic neuropathy (regardless of connection with taking PDE-5 inhibitors including generic Cialis);
- simultaneous treatment with doxazosin, as well as drugs for erectile dysfunction treatment;
- frequent (more than 2 times per week) application in patients with chronic renal failure (creatinine clearance less than 30 mL/min);
- deficiency of lactose, lactose intolerance, glucose-galactose malabsorption.
Cialis Taken with Care
Since there is no data in patients with severe hepatic insufficiency (class C according to a classification of Child-Pugh), caution must be exercised when administering Cialis by this group of patients.
Caution should be exercised when administering Cialis to patients receiving alpha1-blocker, in case of simultaneous use which can lead to symptomatic hypotension in some patients. In a clinical pharmacology study in 18 healthy volunteers who received a single dose of tadalafil (the main component), there was no symptomatic hypotension while tamsulosin introduction.
Diagnosis of erectile dysfunction should include identification of potential cause, appropriate medical examination and treatment determination.
Cialis should be used with caution in patients with a predisposition to priapism (for sickle cell anemia, multiple myeloma or leukemia), or in patients with anatomical deformation of the penis (angulation, cavernous fibrosis or Peyronie’s disease). Also, be careful when simultaneous use potent inhibitors of isoenzyme CYP3A4 (ritonavir saquinavir, ketoconazole, itraconazole, erythromycin), antihypertensives.
